Description

17β-Estradiol 2-Acetate is a high-purity, semi-synthetic steroid derivative, specifically the 2-acetate ester of 17β-estradiol. This compound is a critical pharmaceutical intermediate and reference standard, valued for its precise chemical structure and consistent biological activity profile. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development and quality control of hormonal therapies, diagnostic agents, and biochemical research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of more complex steroidal drugs and hormone analogs.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of estradiol-based products via HPLC, GC, or LC-MS.
• Biochemical Research: Employed in in-vitro and in-vivo studies to investigate estrogen receptor binding, metabolic pathways, and endocrine system functions.
• Diagnostic Reagent Manufacturing: Serves as a raw material in the production of immunoassay kits and other diagnostic tools for hormone level detection.
• Veterinary Medicine: Potential use in the formulation of hormonal treatments for animals.

Basic Information

Product Name	17β-Estradiol 2-Acetate
CAS No.	32162-96-2
Molecular Formula	C20H26O3
Molecular Weight	314.42 g/mol
Synonyms	Estradiol 2-Acetate; 17β-Estradiol 2-acetate; Estr-1,3,5(10)-triene-3,17β-diol 2-acetate; 3,17β-Dihydroxyestra-1,3,5(10)-trien-2-yl acetate; 2-Acetoxyestradiol; NSC 124004
EINECS	Contact for details

Quality Control

Our 17β-Estradiol 2-Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from advanced techniques like HPLC and GC. While not necessarily compendial grade, our quality standards are designed to meet the rigorous demands of pharmaceutical R&D and reference standard applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.