Description

1α-[(Trimethylsilyl)Oxy]-4β-Methylcyclohexane is a specialized organosilicon compound featuring a silyl-protected hydroxyl group on a methylated cyclohexane backbone. This structure makes it a valuable protected intermediate and building block in advanced organic synthesis, particularly where selective deprotection is required. It is primarily utilized by research institutions and industrial R&D departments engaged in the development of pharmaceuticals, agrochemicals, and novel materials.

Application

• Pharmaceutical Intermediate: Serves as a key protected synthon in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used as a building block in the research and production of advanced pesticides, herbicides, and plant growth regulators.
• Organic Synthesis Reagent: Acts as a versatile intermediate in academic and industrial laboratories for constructing complex organic frameworks, leveraging the trimethylsilyl (TMS) protecting group.
• Material Science Research: Employed in the development of specialty chemicals, silicone-based polymers, and other advanced materials requiring specific hydrophobic or steric properties.
• Chemical Standard: Used as a reference standard or analytical reagent in quality control and method development for chromatographic analysis.

Basic Information

Product Name	1α-[(Trimethylsilyl)Oxy]-4β-Methylcyclohexane
CAS No.	32147-24-3
Molecular Formula	C10H22OSi
Molecular Weight	186.37 g/mol
Synonyms	4-Methyl-1-(trimethylsilyloxy)cyclohexane; 1-(Trimethylsiloxy)-4-methylcyclohexane; 4-Methylcyclohexyloxytrimethylsilane; trans-4-Methyl-1-(trimethylsilyloxy)cyclohexane; 1-Trimethylsilyloxy-4-methylcyclohexane; 4-Methyl-1-(trimethylsilyloxy)cyclohexane, mixture of isomers; Cyclohexanol, 4-methyl-, 1-(trimethylsilyl) ether
EINECS	Contact for details

Quality Control

Our 1α-[(Trimethylsilyl)Oxy]-4β-Methylcyclohexane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture ingress, which can compromise product integrity. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Gravity (20°C)	0.85 - 0.90
Refractive Index (20°C)	1.430 - 1.440

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.