Description

Phosphoric Acid 2,3-Bis(Trimethylsiloxy)Propyl 2-[Bis(Trimethylsilyl)Amino]Ethyl(Trimethylsilyl) Ester is a highly specialized organosilicon-protected phosphate derivative, designed for advanced synthetic and process chemistry. This compound is valued for its role as a key intermediate or protecting group reagent in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is essential for chemists and manufacturers requiring precise control over phosphate group reactivity and stability in sensitive reactions.

Application

• Pharmaceutical Intermediate: Used in the synthesis of nucleotide analogs, prodrugs, and other active pharmaceutical ingredients (APIs) where phosphate group protection is required.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, insecticides, and plant growth regulators with modified phosphate functionalities.
• Peptide & Oligonucleotide Chemistry: Acts as a protecting group reagent for phosphate moieties during solid-phase and solution-phase synthesis of biomolecules.
• Material Science Research: Employed in the development of specialty surfactants, flame retardants, and surface-modifying agents with silicon-phosphate hybrid structures.
• Process Chemistry & Catalysis: Utilized as a ligand precursor or a modifying agent in catalytic systems and specialty chemical manufacturing processes.

Basic Information

Product Name	Phosphoric Acid 2,3-Bis(Trimethylsiloxy)Propyl 2-[Bis(Trimethylsilyl)Amino]Ethyl(Trimethylsilyl) Ester
CAS No.	32046-29-0
Molecular Formula	C20H54N1O4P1Si5
Molecular Weight	564.13 g/mol
Synonyms	2-[Bis(trimethylsilyl)amino]ethyl (2,3-bis(trimethylsiloxy)propyl) trimethylsilyl phosphate; Phosphoramidic acid, N-[2-[(2,3-bis[(trimethylsilyl)oxy]propoxy)(trimethylsilyloxy)phosphinyl]oxy]ethyl]-N-(trimethylsilyl)-, trimethylsilyl ester; Tris(trimethylsilyl) Phosphoroamidate Ester; TMS-Protected Phosphoramidate; O,O-Bis(trimethylsiloxy)propyl O'-(N,N-Bis(trimethylsilyl)aminoethyl) Phosphoramidate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of this high-purity synthetic intermediate adheres to stringent quality protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for research and process chemistry. Comprehensive analytical data, including NMR (¹H, ¹³C, ³¹P) and chromatographic profiles (HPLC/GC), are documented. A Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.