Description

3-[4-[[4-[Bis(2-Chloroethyl)Amino]-2,5-Dimethoxy-Phenyl]Methylideneamino]Phenyl]Oxazolidin-2-One is a specialized nitrogen mustard derivative oxazolidinone compound, serving as a critical building block in advanced pharmaceutical research and development. Its molecular architecture, featuring a bis(2-chloroethyl)amino group, makes it a valuable precursor for synthesizing targeted therapeutic agents, particularly in oncology. This high-purity intermediate is essential for research chemists and process development scientists working on novel alkylating agents and prodrugs within the pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel nitrogen mustard-based chemotherapeutic agents and targeted cancer therapies.
• Anticancer Drug Research: Serves as a core scaffold for developing new alkylating agents that target DNA replication in cancer cells.
• Prodrug Development: Used in the design and synthesis of prodrugs that require specific activation mechanisms within the body.
• Medicinal Chemistry: A valuable building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Bioconjugation: Potential use in creating antibody-drug conjugates (ADCs) due to its reactive chloroethyl groups.
• Academic & Institutional Research: Employed in biochemical and pharmacological studies investigating mechanisms of alkylation and cytotoxicity.

Basic Information

Product Name	3-[4-[[4-[Bis(2-Chloroethyl)Amino]-2,5-Dimethoxy-Phenyl]Methylideneamino]Phenyl]Oxazolidin-2-One
CAS No.	31847-13-9
Molecular Formula	C22H25Cl2N3O4
Molecular Weight	466.36 g/mol
Synonyms	2-Oxazolidinone, 3-[4-[[[4-[bis(2-chloroethyl)amino]-2,5-dimethoxyphenyl]methylene]amino]phenyl]-; 3-(4-((4-(Bis(2-chloroethyl)amino)-2,5-dimethoxybenzylidene)amino)phenyl)oxazolidin-2-one; Oxazolidin-2-one derivative of nitrogen mustard; Nitrogen mustard oxazolidinone; Chlorambucil oxazolidinone analog; Mustard-oxazolidinone hybrid; DNA alkylating agent intermediate
EINECS	Contact for details

Quality Control

Our production of 3-[4-[[4-[Bis(2-Chloroethyl)Amino]-2,5-Dimethoxy-Phenyl]Methylideneamino]Phenyl]Oxazolidin-2-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research applications. All material is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.