Description

[1S,2S,(+)]-9'α-Acetyloxy-4'B,8'Aβ,9',10'-Tetrahydro-3'β,10'β-Dihydroxy-2,4'Bα,7',8'-Tetramethylspiro[Cyclopropane-1,2'(1'H)-Phenanthrene]-1',4',6'(3'H,5'H)-Trione is a high-purity, complex spirocyclic diterpenoid derivative with significant potential as a key chiral intermediate in advanced organic synthesis. Its intricate stereochemistry and functional groups make it a valuable building block for pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. This compound is essential for R&D chemists and process development scientists working in pharmaceutical, agrochemical, and fine chemical industries who require highly specific stereochemical control in their synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for steroids and complex polycyclic molecules.
• Organic Synthesis Research: Used as a sophisticated building block in academic and industrial laboratories for constructing complex natural product analogs and exploring new chemical spaces.
• Agrochemical Development: Acts as a potential precursor in the synthesis of novel, biologically active compounds for crop protection and pest management research.
• Asymmetric Catalysis Studies: Employed as a substrate or ligand precursor in the development and testing of new asymmetric catalytic systems due to its multiple stereocenters.
• Reference Standard: Used as a high-purity analytical standard for method development and quality control in laboratories analyzing complex diterpenoid structures.
• Material Science Research: Investigated as a monomer or precursor for creating novel polymers and advanced materials with specific chiral properties.

Basic Information

Product Name	[1S,2S,(+)]-9'α-Acetyloxy-4'B,8'Aβ,9',10'-Tetrahydro-3'β,10'β-Dihydroxy-2,4'Bα,7',8'-Tetramethylspiro[Cyclopropane-1,2'(1'H)-Phenanthrene]-1',4',6'(3'H,5'H)-Trione
CAS No.	31745-31-0
Molecular Formula	C24H28O7
Molecular Weight	428.48 g/mol
Synonyms	(+)-9'-Acetoxy-4',8',9',10'-tetrahydro-3',10'-dihydroxy-2,4',7',8'-tetramethylspiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4',6'(3'H,5'H)-trione; 9'-Acetyloxy-4',8',9',10'-tetrahydro-3',10'-dihydroxy-2,4',7',8'-tetramethylspiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4',6'(3'H,5'H)-trione; CAS 31745-31-0; Spiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4',6'(3'H,5'H)-trione derivative; (1S,2S)-9'-Acetyloxy-4',8',9',10'-tetrahydro-3',10'-dihydroxy-2,4',7',8'-tetramethyl-; (1S,2S)-(+)-form of the diterpenoid derivative.
EINECS	Contact for details

Quality Control

Our [1S,2S,(+)]-9'α-Acetyloxy-4'B,8'Aβ,9',10'-Tetrahydro-3'β,10'β-Dihydroxy-2,4'Bα,7',8'-Tetramethylspiro[Cyclopropane-1,2'(1'H)-Phenanthrene]-1',4',6'(3'H,5'H)-Trione is manufactured under strict quality management systems. Products undergo rigorous analytical testing, including chiral purity verification, to ensure consistent identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing lot-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); ensure the container is sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee ([1S,2S] enantiomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.