Description

Methylatropine is a quaternary ammonium derivative of atropine, functioning as a potent anticholinergic agent. Its primary commercial value lies in its use as a key pharmaceutical intermediate and reference standard in the development and quality control of antispasmodic and mydriatic medications. This compound is essential for manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity building blocks for active pharmaceutical ingredient (API) synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of advanced anticholinergic drugs.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control (QC) testing of related pharmaceutical products.
• Biochemical Research: Employed in pharmacological studies to investigate muscarinic acetylcholine receptor (mAChR) antagonism and related physiological pathways.
• Active Pharmaceutical Ingredient (API) Development: A key starting material for formulating experimental and commercial antispasmodic formulations.
• Fine Chemical Synthesis: Utilized in organic synthesis to create more complex molecules with targeted biological activity.

Basic Information

Product Name	Methylatropine
CAS No.	31610-87-4
Molecular Formula	C18H26NO3+
Molecular Weight	304.41 g/mol (as cation)
Synonyms	Atropine Methobromide; Atropine Methyl Bromide; 8-Methylatropinium Bromide; Tropine Tropate Methyl Bromide; (8R)-Tropanyl (2S)-3-hydroxy-2-phenylpropanoate methyl bromide; DL-Hyoscyamine Methyl Bromide; Methylatropine Bromide; NSC 406042
EINECS	Contact for details

Quality Control

Our Methylatropine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates and research chemicals. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.