Description

1-H-Pyrazolo[3,4-B]Pyridin-4-Ol is a high-purity heterocyclic organic compound that serves as a critical advanced pharmaceutical intermediate and a versatile building block in medicinal chemistry. Its fused pyrazolopyridine core structure makes it a valuable scaffold for the research and development of novel active pharmaceutical ingredients (APIs). This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing target molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor research.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Serves as a precursor in the research of new herbicides, fungicides, and plant growth regulators.
• Organic Synthesis: A versatile reagent for constructing complex nitrogen-containing heterocycles in academic and industrial laboratories.
• Biochemical Research: Potential use as a ligand or probe in biochemical assays and enzyme inhibition studies.

Basic Information

Product Name	1-H-Pyrazolo[3,4-B]Pyridin-4-Ol
CAS No.	31591-86-3
Molecular Formula	C6H5N3O
Molecular Weight	135.12 g/mol
Synonyms	1H-Pyrazolo[3,4-b]pyridin-4-ol; 4-Hydroxy-1H-pyrazolo[3,4-b]pyridine; 4-Hydroxypyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridin-4(5H)-one (tautomer); Pyrazolo[3,4-b]pyridin-4-ol; 31591-86-3; 4-Pyrazolopyridinol
EINECS	Contact for details

Quality Control

Our 1-H-Pyrazolo[3,4-B]Pyridin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.