Description

n-Isopropyl-3-Isopropylthio-L-Alanine Isopropyl Ester is a specialized, high-purity chiral building block and intermediate of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which incorporates both a protected amino acid ester and a thioether functional group, enabling precise stereochemical control in complex molecule construction. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, peptides, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in peptide-mimetic and sulfur-containing drug candidates.
• Agrochemical Synthesis: Used in the construction of advanced, stereochemically defined intermediates for new-generation herbicides, fungicides, and insecticides.
• Peptide Chemistry: Serves as a protected, non-natural amino acid derivative for the solid-phase or solution-phase synthesis of modified peptides and peptidomimetics.
• Ligand and Catalyst Development: Employed as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and constructing complex molecular libraries.
• Fine Chemical Production: Utilized in the custom synthesis of high-value, specialty chemicals for various technological applications.

Basic Information

Product Name	n-Isopropyl-3-Isopropylthio-L-Alanine Isopropyl Ester
CAS No.	31552-14-4
Molecular Formula	C12H25NO2S
Molecular Weight	247.40 g/mol
Synonyms	L-Alanine, N-(1-methylethyl)-3-[(1-methylethyl)thio]-, 1-methylethyl ester; Isopropyl 3-(isopropylthio)-N-isopropyl-L-alaninate; (S)-Isopropyl 3-(isopropylthio)-2-(isopropylamino)propanoate; 3-(Isopropylthio)-N-isopropyl-L-alanine isopropyl ester; Alanine derivative CAS 31552-14-4; Chiral alanine ester intermediate; N-Isopropyl-3-isopropylthioalanine isopropyl ester
EINECS	Contact for details

Quality Control

Our n-Isopropyl-3-Isopropylthio-L-Alanine Isopropyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.