Description

1-Ethoxy-2-Methyl-1-(Trimethylsiloxy)-1-Propene is a specialized organosilicon reagent featuring a silyl enol ether functional group. This compound matters as a versatile and highly reactive intermediate for introducing the 1-ethoxy-2-methylpropenyl moiety in complex organic syntheses. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures, particularly in the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, flavors, and fragrances requiring specific alkene functionality.
• Polymer & Material Science: Employed in the development of novel polymers, silicone-based materials, and functional coatings.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and catalysis research.
• Cross-Coupling Reactions: Acts as a coupling partner in transition-metal catalyzed reactions to form carbon-carbon bonds.

Basic Information

Product Name	1-Ethoxy-2-Methyl-1-(Trimethylsiloxy)-1-Propene
CAS No.	31469-16-6
Molecular Formula	C9H20O2Si
Molecular Weight	188.34 g/mol
Synonyms	1-Ethoxy-2-methyl-1-(trimethylsilyloxy)-1-propene; 1-Ethoxy-2-methyl-1-(trimethylsiloxy)propene; 1-Propene, 1-ethoxy-2-methyl-1-(trimethylsiloxy)-; (1-Ethoxy-2-methylprop-1-en-1-yloxy)trimethylsilane; Trimethyl[(1-ethoxy-2-methylprop-1-en-1-yl)oxy]silane; Silyl enol ether of ethyl 2-methylpropanoate (derivative); TMS enol ether of ethyl isobutyrate
EINECS	Contact for details

Quality Control

Our 1-Ethoxy-2-Methyl-1-(Trimethylsiloxy)-1-Propene is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C to maximize stability. This material is hygroscopic (moisture-sensitive) and easily oxidized; containers must be kept sealed and purged with inert gas after each use to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.