Description

1β-(Trimethylsilyl)Oxy-4α-Benzyloxycyclohexane is a high-value, organosilicon-protected intermediate used in sophisticated organic synthesis. This compound is critical for constructing complex molecular architectures where selective protection and deprotection of hydroxyl groups are required. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the production of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates, particularly those containing functionalized cyclohexane rings.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Academic & Industrial Research: Serves as a versatile reagent in methodological studies for new synthetic routes involving silicon-based protecting group strategies.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high-purity, stereochemically defined intermediates.
• Process Chemistry Development: Used to optimize scalable synthetic pathways in pilot plants and for establishing robust manufacturing processes.

Basic Information

Product Name	1β-(Trimethylsilyl)Oxy-4α-Benzyloxycyclohexane
CAS No.	31447-55-9
Molecular Formula	C16H26O2Si
Molecular Weight	278.47 g/mol
Synonyms	Cyclohexanol, 4-(benzyloxy)-1-[(trimethylsilyl)oxy]-, (1R,4R)-rel-; (1R,4R)-4-(Benzyloxy)-1-[(trimethylsilyl)oxy]cyclohexane; 1-β-(Trimethylsilyl)oxy-4-α-benzyloxycyclohexane; 1-TMS-Oxy-4-Bn-Oxy-cyclohexane; 1β-TMS-Oxy-4α-Bn-Oxy-cyclohexane; 4α-Benzyloxy-1β-(trimethylsilyloxy)cyclohexane; 1-(Trimethylsiloxy)-4-benzyloxycyclohexane
EINECS	Contact for details

Quality Control

Every batch of 1β-(Trimethylsilyl)Oxy-4α-Benzyloxycyclohexane is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the exacting standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and other critical parameters as per client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or moisture should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.