Description

1,2-Cyclopropanedicarboxylicacid, 1-Ethyl Ester, (1R,2R)-Rel- is a high-purity, stereochemically defined chiral building block of significant value in advanced organic synthesis. This compound matters because it provides a rigid, functionalized cyclopropane scaffold essential for constructing complex molecules with precise three-dimensional architecture. It is primarily needed by research chemists and process development teams in the pharmaceutical and agrochemical industries for applications such as asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring a constrained cyclopropane moiety.
• Asymmetric Catalysis Research: Used as a starting material or ligand precursor in the development of new stereoselective catalytic reactions.
• Agrochemical Synthesis: Serves as a building block for creating novel pesticides and herbicides with enhanced biological activity and selectivity.
• Material Science: Potential monomer or cross-linking agent for the development of specialized polymers with unique thermal or mechanical properties.
• Academic & Industrial R&D: Employed in methodological studies and the exploration of new chemical spaces in synthetic organic chemistry laboratories worldwide.

Basic Information

Product Name	1,2-Cyclopropanedicarboxylicacid, 1-Ethyl Ester, (1R,2R)-Rel-
CAS No.	31420-66-3
Molecular Formula	C8H12O4
Molecular Weight	172.18 g/mol
Synonyms	(1R,2R)-rel-1-Ethyl 1,2-cyclopropanedicarboxylate; Ethyl (1R,2R)-rel-1,2-cyclopropanedicarboxylate; 1-Ethyl (1R,2R)-rel-1,2-cyclopropanedicarboxylate; (1R,2R)-rel-1,2-Cyclopropanedicarboxylic Acid 1-Ethyl Ester; 1,2-Cyclopropanedicarboxylic acid, 1-ethyl ester, (1R,2R)-rel-; Ethyl (1R,2R)-1,2-cyclopropanedicarboxylate (relative configuration)
EINECS	Contact for details

Quality Control

Our 1,2-Cyclopropanedicarboxylicacid, 1-Ethyl Ester, (1R,2R)-Rel- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting R&D and process chemistry standards. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric/excess data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.