Description

2-Chloro-5-Nitronicotinonitrile is a versatile and high-value nitrile-substituted pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both chloro and nitro functional groups on the pyridine ring, makes it an essential building block for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its reactive nitrile and nitro groups.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and liquid crystals.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic aromatic substitutions, and cyclization reactions to create complex molecular architectures.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic pathways and heterocyclic chemistry.

Basic Information

Product Name	2-Chloro-5-Nitronicotinonitrile
CAS No.	31309-08-7
Molecular Formula	C6H2ClN3O2
Molecular Weight	183.55 g/mol
Synonyms	5-Nitro-2-chloronicotinonitrile; 2-Chloro-5-nitropyridine-3-carbonitrile; 3-Cyano-2-chloro-5-nitropyridine; 2-Chloro-5-nitro-3-pyridinecarbonitrile; Nicotinonitrile, 2-chloro-5-nitro-; 2-Chloro-5-nitro-3-cyanopyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-Nitronicotinonitrile is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to store the material under an inert atmosphere for long-term preservation. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.