Description

n-(2,2,2-Trifluoroethylidene)Cyclohexanamine is a specialized fluorinated amine building block of significant interest in advanced organic synthesis. Its unique structure, featuring a trifluoroethylidene group attached to a cyclohexylamine, makes it a valuable precursor for creating novel compounds with enhanced properties. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors. It enables the synthesis of complex molecules where the introduction of fluorine atoms can dramatically alter biological activity, metabolic stability, and lipophilicity.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drugs targeting the central nervous system, oncology, and metabolic diseases.
• Agrochemical Research: Used in creating advanced herbicides, fungicides, and insecticides where the fluorine moiety can improve efficacy, environmental stability, and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis, leveraging the steric and electronic influence of the cyclohexyl and trifluoromethyl groups.
• Material Science Precursor: Employed in the research of specialty polymers and advanced materials, where fluorinated amines can impart unique surface properties, chemical resistance, or optical characteristics.
• Fluorine Chemistry Research: An essential compound for academic and industrial research focused on exploring new reactions and methodologies in organofluorine chemistry.

Basic Information

Product Name	n-(2,2,2-Trifluoroethylidene)Cyclohexanamine
CAS No.	31185-49-6
Molecular Formula	C8H12F3N
Molecular Weight	179.18 g/mol
Synonyms	N-(2,2,2-Trifluoroethylidene)cyclohexanamine; 1-[(2,2,2-Trifluoroethylidene)amino]cyclohexane; Cyclohexanamine, N-(2,2,2-trifluoroethylidene)-; 2,2,2-Trifluoro-N-cyclohexylideneethanamine; N-(Trifluoroethylidene)cyclohexylamine; Trifluoroacetaldehyde cyclohexylimine
EINECS	Contact for details

Quality Control

Our n-(2,2,2-Trifluoroethylidene)Cyclohexanamine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including GC, HPLC, and NMR to confirm identity and purity. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.