Description

3-Chlorodihydrofuran-2(3H)-One is a versatile chlorinated lactone derivative that serves as a key chiral building block and reactive intermediate in advanced organic synthesis. Its unique structure, featuring a reactive carbonyl and a chlorine substituent, makes it invaluable for constructing complex heterocyclic frameworks and fine chemicals. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and high-value intermediates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of chiral drug candidates, particularly for antiviral and central nervous system (CNS) active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where its chlorinated lactone structure contributes to biological activity.
• Fine Chemical Manufacturing: Serves as a versatile building block for creating complex molecules used in flavors, fragrances, and advanced material science.
• Organic Synthesis Reagent: Employed in ring-opening and ring-closing reactions, as well as nucleophilic substitution reactions, to introduce functional complexity.
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialized polymers and resins with tailored properties.
• Academic & Industrial R&D: A valuable tool for methodological development and exploring new synthetic pathways in research laboratories.

Basic Information

Product Name	3-Chlorodihydrofuran-2(3H)-One
CAS No.	31167-90-5
Molecular Formula	C4H5ClO2
Molecular Weight	120.53 g/mol
Synonyms	3-Chlorotetrahydrofuran-2-one; 3-Chloro-2-oxotetrahydrofuran; 3-Chloro-γ-butyrolactone; 3-Chlorodihydro-2(3H)-furanone; 3-Chlorooxolan-2-one; α-Chloro-γ-butyrolactone; NSC 403119
EINECS	Contact for details

Quality Control

Our 3-Chlorodihydrofuran-2(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%
Specific Rotation (if applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.