Description

Bis(Trimethylsilyloxy)Phosphinyloxy(Trimethylsilyloxymethyl)Acetic Acid Trimethylsilyl Ester is a specialized organosilicon reagent featuring multiple silyl-protecting groups. This compound is highly valued for its role as a key intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on nucleoside chemistry, prodrug development, and the synthesis of phosphate ester analogs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of antiviral and anticancer nucleoside prodrugs.
• Agrochemical Synthesis: Used in the development of novel phosphate-based pesticides and herbicides.
• Chemical Research: Serves as a versatile phosphorylating and silylating agent in organic synthesis laboratories.
• Prodrug Development: Facilitates the creation of masked phosphate groups to improve drug bioavailability and stability.
• Material Science: Potential intermediate for creating specialized silicon-containing polymers and coatings.

Basic Information

Product Name	Bis(Trimethylsilyloxy)Phosphinyloxy(Trimethylsilyloxymethyl)Acetic Acid Trimethylsilyl Ester
CAS No.	31038-14-9
Molecular Formula	C14H37NO7PSi4
Molecular Weight	483.85 g/mol
Synonyms	Acetic acid, [(bis(trimethylsilyloxy)phosphinyl)oxy](trimethylsilyloxymethyl)-, trimethylsilyl ester; Trimethylsilyl [(bis(trimethylsilyloxy)phosphinyl)oxy](trimethylsilyloxymethyl)acetate; TMS-Bis-TMS-PO-OMTMS-Acetate; NSC 339063; Acetic acid, [bis(trimethylsiloxy)phosphinyl]oxy(trimethylsiloxymethyl)-, trimethylsilyl ester
EINECS	Contact for details

Quality Control

Our production of Bis(Trimethylsilyloxy)Phosphinyloxy(Trimethylsilyloxymethyl)Acetic Acid Trimethylsilyl Ester adheres to stringent quality protocols suitable for research and development applications. Each batch is analyzed to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.