Description

3-[Bis(Trimethylsilyloxy)Phosphinyloxy]-2-(Trimethylsilyloxy)Propionic Acid Trimethylsilyl Ester is a highly functionalized organosilicon reagent, primarily valued for its role as a versatile protecting group and intermediate in complex organic synthesis. Its multi-silylated structure offers unique reactivity and stability, making it a critical component for constructing sensitive molecules under controlled conditions. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular assembly is paramount.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly for protecting hydroxyl and carboxylic acid groups during multi-step reactions.
• Peptide Synthesis: Used as a specialized reagent for the protection of amino acid side chains, enabling the synthesis of complex peptides and peptide mimetics.
• Agrochemical Development: Intermediate in the production of advanced herbicides, fungicides, and plant growth regulators requiring sophisticated silicon chemistry.
• Organometallic Chemistry: Serves as a precursor or ligand modifier in the preparation of catalysts and other organometallic complexes.
• Material Science Research: Employed in the development of novel silicone-based polymers, coatings, and hybrid organic-inorganic materials.
• Chemical Derivatization: Used in analytical chemistry to derivative polar compounds for Gas Chromatography (GC) or Mass Spectrometry (MS) analysis, improving volatility and detection.

Basic Information

Item	Information
Product Name	3-[Bis(Trimethylsilyloxy)Phosphinyloxy]-2-(Trimethylsilyloxy)Propionic Acid Trimethylsilyl Ester
CAS No.	31038-13-8
Molecular Formula	C15H39NO7PSi4
Molecular Weight	497.85 g/mol
Synonyms	2-(Trimethylsilyloxy)-3-[bis(trimethylsilyloxy)phosphinyloxy]propionic acid trimethylsilyl ester; Tris(trimethylsilyl) 2-(trimethylsilyloxy)-3-[bis(trimethylsilyloxy)phosphinyloxy]propionate; O-Phosphono-3-(trimethylsilyloxy)-2-(trimethylsilyloxy)propionic acid tris(trimethylsilyl) ester; Silylating agent 31038-13-8; TMS-protected phosphonate ester; Multi-silylated phosphonopropionate
EINECS	Contact for details

Quality Control

Our production of 3-[Bis(Trimethylsilyloxy)Phosphinyloxy]-2-(Trimethylsilyloxy)Propionic Acid Trimethylsilyl Ester adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We are committed to meeting the exacting standards required for research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after initial opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.