Description

Diethyl (4-Biphenylylmethyl)Phosphonate is a high-value organophosphorus compound, specifically a phosphonate ester, that serves as a critical synthetic intermediate in advanced organic chemistry. Its primary commercial value lies in its role as a versatile building block for constructing complex molecular architectures, particularly in pharmaceutical and materials science research. This compound is essential for chemists and manufacturers engaged in the development of active pharmaceutical ingredients (APIs), specialty chemicals, and advanced functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its phosphonate moiety for biological activity.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized phosphine-based ligands used in asymmetric catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and flame-retardant additives due to its biphenyl and phosphonate structure.
• Chemical Biology Probes: Utilized to develop enzyme inhibitors and molecular probes for studying biochemical pathways.
• Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical and custom synthesis houses serving the pharmaceutical and biotechnology industries.

Basic Information

Product Name	Diethyl (4-Biphenylylmethyl)Phosphonate
CAS No.	30818-70-3
Molecular Formula	C17H21O3P
Molecular Weight	304.32 g/mol
Synonyms	Diethyl (4-Phenylbenzyl)Phosphonate; Diethyl [(1,1'-Biphenyl)-4-ylmethyl]Phosphonate; (4-Biphenylylmethyl)Phosphonic Acid Diethyl Ester; Phosphonic Acid, P-[(1,1'-Biphenyl)-4-ylmethyl]-, Diethyl Ester; Diethyl (4-Biphenylmethyl)Phosphonate; 4-(Diethoxyphosphorylmethyl)biphenyl
EINECS	Contact for details

Quality Control

Our Diethyl (4-Biphenylylmethyl)Phosphonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.