Description

Methyl 1-O,3-O,4-O,5-o-Tetrakis(Trimethylsilyl)-L-Sorbopyranoside is a fully protected derivative of L-sorbose, a key sugar intermediate, where the hydroxyl groups are shielded by trimethylsilyl (TMS) ether groups. This compound is critically important as a versatile building block and chiral synthon in advanced organic synthesis, particularly for the preparation of complex carbohydrates and nucleoside analogs. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, protected sugar intermediates for stereoselective synthesis and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a protected chiral precursor for the synthesis of novel antiviral, anticancer, and antibiotic agents.
• Carbohydrate Chemistry: A crucial building block for the stepwise, regioselective construction of complex oligosaccharides and glycoconjugates.
• Nucleoside Analog Synthesis: Used in the preparation of modified nucleosides for potential therapeutic applications and biochemical probes.
• Chiral Pool Synthesis: Provides a readily available source of chirality from the L-sugar series for asymmetric synthesis in fine chemicals.
• Agrochemical Research: Employed in the development of new, biologically active compounds with specific stereochemical requirements.
• Process Development: Acts as a standardized intermediate for scaling up synthetic routes in pilot plants and commercial production.

Basic Information

Product Name	Methyl 1-O,3-O,4-O,5-o-Tetrakis(Trimethylsilyl)-L-Sorbopyranoside
CAS No.	30788-70-6
Molecular Formula	C19H46O6Si4
Molecular Weight	482.90 g/mol
Synonyms	Methyl 1,3,4,5-Tetra-O-trimethylsilyl-L-sorbopyranoside; Methyl L-Sorbopyranoside 1,3,4,5-Tetrakis(trimethylsilyl) Ether; 1,3,4,5-Tetra-O-trimethylsilyl-L-sorbose Methyl Glycoside; L-Sorbose, methyl glycoside, 1,3,4,5-tetrakis-O-(trimethylsilyl)-; Methyl α-L-Sorbopyranoside 1,3,4,5-Tetra-O-TMS; Protected L-Sorbose Methyl Glycoside; TMS-L-Sorbose Methyl Glycoside
EINECS	Contact for details

Quality Control

Every batch of Methyl 1-O,3-O,4-O,5-o-Tetrakis(Trimethylsilyl)-L-Sorbopyranoside is produced and tested under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing specific batch results for purity (by HPLC/NMR), identity confirmation, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical: 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.