Description

Ethyl 2-(4-Bromophenyl)-2-Hydroxyacetate is a versatile chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its structure, featuring both a bromoaryl group and a hydroxyacetate moiety, makes it a valuable precursor for constructing complex molecules with high stereochemical control. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs), β-blockers, and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific stereochemistry.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, such as in hydrogenation or cross-coupling reactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where precise molecular architecture is critical.
• Academic and R&D: A valuable compound for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	Ethyl 2-(4-Bromophenyl)-2-Hydroxyacetate
CAS No.	30565-53-8
Molecular Formula	C10H11BrO3
Molecular Weight	259.10 g/mol
Synonyms	Ethyl (4-Bromophenyl)(hydroxy)acetate; 2-Hydroxy-2-(4-bromophenyl)acetic Acid Ethyl Ester; 4-Bromomandelic Acid Ethyl Ester; Ethyl 4-Bromomandelate; α-Hydroxy-4-bromobenzeneacetic Acid Ethyl Ester; (4-Bromophenyl)(hydroxy)acetic Acid Ethyl Ester; Ethyl α-Hydroxy-4-bromophenylacetate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(4-Bromophenyl)-2-Hydroxyacetate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.