Description

8-Aminomethyl-1,4-dioxaspiro[4.5]decane is a versatile spirocyclic amine derivative featuring a protected ketone group. This compound matters as a valuable chiral building block and intermediate in sophisticated organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of complex drug molecules, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its spirocyclic structure for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, flavors, and fragrances.
• Material Science Research: Building block for novel polymers and functional materials with specific thermal or mechanical properties.
• Academic & Industrial R&D: Used in chemical research for methodology development and exploring new synthetic pathways.

Basic Information

Product Name	8-Aminomethyl-1,4-dioxaspiro[4.5]decane
CAS No.	30482-25-8
Molecular Formula	C10H19NO2
Molecular Weight	185.26 g/mol
Synonyms	8-(Aminomethyl)-1,4-dioxaspiro[4.5]decane; 1,4-Dioxaspiro[4.5]decane-8-methanamine; 8-Aminomethyl-1,4-dioxa-spiro[4.5]decane; 4-(Aminomethyl)cyclohexanone ethylene ketal; Cyclohexanone, 4-(aminomethyl)-, ethylene ketal; (1,4-Dioxaspiro[4.5]decan-8-yl)methanamine
EINECS	Contact for details

Quality Control

Our 8-Aminomethyl-1,4-dioxaspiro[4.5]decane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.