Description

1,4-Dioxaspiro[4.5]Decane-8-Carboxamide is a high-purity, versatile spirocyclic building block and intermediate of significant interest in advanced organic synthesis. Its unique structural motif, featuring a fused dioxolane and cyclohexane ring system, makes it a valuable scaffold for constructing complex molecules with specific stereochemistry and functionality. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas requiring complex, three-dimensional molecular architectures.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the spirocyclic structure can contribute to unique biological activity and stability.
• Advanced Material Precursor: Serves as a monomer or intermediate in the synthesis of specialty polymers, ligands for catalysis, and other functional materials.
• Organic Synthesis Reagent: A versatile starting material in academic and industrial R&D for constructing complex natural product analogs and exploring new chemical spaces.
• Chiral Auxiliary/Resolution Agent: Potential use in asymmetric synthesis due to its inherent chirality and rigid structure.

Basic Information

Product Name	1,4-Dioxaspiro[4.5]Decane-8-Carboxamide
CAS No.	30482-24-7
Molecular Formula	C9H15NO3
Molecular Weight	185.22 g/mol
Synonyms	8-Carbamoyl-1,4-dioxaspiro[4.5]decane; 1,4-Dioxaspiro[4.5]decane-8-carboxylic acid amide; 8-Carboxamido-1,4-dioxaspiro[4.5]decane; Spiro[1,3-dioxolane-2,1'-cyclohexane]-4'-carboxamide; 1,4-Dioxaspiro[4.5]decan-8-ylcarboxamide; 30482-24-7; 1,4-Dioxaspiro[4.5]decane-8-carboxamide
EINECS	Contact for details

Quality Control

Our 1,4-Dioxaspiro[4.5]Decane-8-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.