Description

Clinofibrate is a synthetic organic compound belonging to the class of fibrates, which are known for their lipid-modulating properties. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the synthesis of active pharmaceutical ingredients (APIs) targeting metabolic disorders. It serves as an essential building block for medicinal chemists and manufacturers in the life sciences sector requiring reliable, specification-grade materials.

Application

• Pharmaceutical Intermediate: Primary use as a key synthetic precursor in the production of lipid-regulating agents and fibrate-class APIs.
• Biochemical Research: Utilized in in vitro and in vivo studies to investigate mechanisms of action related to peroxisome proliferator-activated receptor (PPAR) modulation.
• Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical laboratories.
• Process Chemistry: Employed in route scouting and optimization for the scalable synthesis of target drug molecules.
• Academic Research: Used in university and institutional labs for medicinal chemistry projects and pharmacological profiling.

Basic Information

Product Name	Clinofibrate
CAS No.	30299-08-2
Molecular Formula	C18H18Cl2O3
Molecular Weight	353.24 g/mol
Synonyms	2-(4'-(p-Chlorophenoxy)phenoxy)-2-methylpropionic Acid Isopropyl Ester; CLY-503; Isopropyl 2-[4-(4-chlorophenoxy)phenoxy]-2-methylpropionate; 2-[4-(4-Chlorophenoxy)phenoxy]-2-methylpropanoic Acid 1-Methylethyl Ester; 2-Methyl-2-[4-(4-chlorophenoxy)phenoxy]propionic Acid Isopropyl Ester; Propanoic acid, 2-[4-(4-chlorophenoxy)phenoxy]-2-methyl-, 1-methylethyl ester
EINECS	Contact for details

Quality Control

Our Clinofibrate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) documenting all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.