Description

Propionic Acid, 2-Isocyanato-, Methyl Ester, D- (8Ci) is a specialized chiral isocyanate derivative, a key building block for synthesizing optically active compounds. Its value lies in its ability to introduce a reactive isocyanate group and a chiral center into target molecules, enabling the creation of high-value, stereochemically defined products. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors who require precise molecular architecture for applications like chiral catalysts, liquid crystals, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and drug candidates.
• Chiral Catalyst Synthesis: Used as a precursor for constructing sophisticated ligands and organocatalysts in asymmetric synthesis.
• Advanced Polymer Chemistry: Serves as a monomer or cross-linking agent for producing specialty polyurethanes and polyureas with tailored optical or mechanical properties.
• Liquid Crystal Development: Incorporated into the molecular structure of chiral liquid crystals for display technologies and optical devices.
• Agrochemical Research: Employed in the development of chiral pesticides and herbicides where specific stereochemistry impacts biological activity.
• Peptide & Protein Modification: Utilized for site-specific labeling or conjugation of biomolecules via reaction with amino groups.
• Analytical Chemistry: Acts as a chiral derivatizing agent for the separation and analysis of enantiomers by chromatography.

Basic Information

Item	Detail
Product Name	Propionic Acid, 2-Isocyanato-, Methyl Ester, D- (8Ci)
CAS No.	30293-81-3
Molecular Formula	C5H7NO3
Molecular Weight	129.11 g/mol
Synonyms	(R)-2-Isocyanatopropionic Acid Methyl Ester; D-2-Isocyanatopropionic Acid Methyl Ester; Methyl (R)-2-Isocyanatopropionate; (R)-Methyl 2-Isocyanatopropanoate; (R)-Methyl 2-isocyanatopropionate; (2R)-2-Isocyanatopropionic Acid Methyl Ester; (+)-Methyl 2-Isocyanatopropionate; D-Form
EINECS	Contact for details

Quality Control

Our Propionic Acid, 2-Isocyanato-, Methyl Ester, D- (8Ci) is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure high enantiomeric excess (e.e.) and chemical purity. Certificates of Analysis (COA) detailing specific results for identity, assay, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent degradation and maintain reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.