Description

N,N'-Di-Boc-L-Lysine Hydroxysuccinimide Ester is a high-purity, protected amino acid derivative widely used as a critical building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring precise, high-yield coupling reactions under mild conditions. It is primarily utilized in the pharmaceutical, biotechnology, and life sciences sectors for the development of novel therapeutic peptides, diagnostic agents, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key reagent for the efficient, racemization-free incorporation of lysine residues with orthogonal side-chain protection.
• Solution-Phase Peptide Chemistry: Enables the synthesis of complex peptide fragments and small proteins in solution.
• Bioconjugation and Labeling: Used to attach peptides, labels, or functional groups to other biomolecules (e.g., proteins, antibodies, surfaces) via amine-reactive chemistry.
• Pharmaceutical Intermediate: Serves as a crucial intermediate in the research and development of peptide-based active pharmaceutical ingredients (APIs).
• Proteomics Research: Employed in the synthesis of custom peptides for antibody production, enzyme substrates, and inhibitors.
• Material Science: Facilitates the creation of peptide-functionalized polymers and biomaterials for advanced applications.

Basic Information

Product Name	N,N'-Di-Boc-L-Lysine Hydroxysuccinimide Ester
CAS No.	30189-36-7
Molecular Formula	C22H37N3O8
Molecular Weight	471.55 g/mol
Synonyms	Nα,Nε-Bis(tert-butoxycarbonyl)-L-lysine N-hydroxysuccinimide ester; Nα,Nε-Di-Boc-L-lysine N-succinimidyl ester; Nα,Nε-Di-Boc-L-lysine OSuc; Nα,Nε-Di-Boc-L-lysine N-hydroxysuccinimide ester; Nα,Nε-Di-Boc-L-lysine succinimidyl ester; (S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid 2,5-dioxopyrrolidin-1-yl ester; Boc-Lys(Boc)-OSu; DiBoc-Lys-OSu
EINECS	Contact for details

Quality Control

Our N,N'-Di-Boc-L-Lysine Hydroxysuccinimide Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for sensitive research and production applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and residual solvent levels is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.