Description

Diethyl 3-Oxopropylphosphonate is a versatile organophosphorus compound, specifically a β-ketophosphonate, that serves as a critical building block in organic synthesis. Its primary value lies in its role as a key reagent in the Horner-Wadsworth-Emmons (HWE) olefination reaction, enabling the efficient and stereoselective synthesis of α,β-unsaturated carbonyl compounds. This makes it an indispensable material for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity intermediates for complex molecule construction.

Application

• Pharmaceutical Intermediate Synthesis: A crucial reagent for constructing olefin linkages in active pharmaceutical ingredients (APIs) and drug candidates via the Horner-Wadsworth-Emmons reaction.
• Agrochemical Manufacturing: Used in the synthesis of complex molecules for herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a key building block for fragrances, flavors, and specialty polymers requiring specific alkene geometries.
• Material Science Research: Employed in the development of novel organic materials, ligands for catalysis, and functionalized monomers.
• Academic & R&D Laboratories: A staple reagent for methodology development and the synthesis of complex natural products and novel organic structures.

Basic Information

Item	Details
Product Name	Diethyl 3-Oxopropylphosphonate
CAS No.	3986-95-6
Molecular Formula	C7H15O4P
Molecular Weight	194.16 g/mol
Synonyms	3-Oxopropylphosphonic Acid Diethyl Ester; Diethyl (3-Oxopropyl)phosphonate; Diethyl 3-Oxopropylphosphonate; 3-Oxopropylphosphonic Acid Diethyl Ester; (3-Oxopropyl)phosphonic Acid Diethyl Ester; Diethyl 3-Oxopropylphosphonate; Diethyl β-Ketopropylphosphonate; β-Ketopropylphosphonic Acid Diethyl Ester
EINECS	223-632-8

Quality Control

Our Diethyl 3-Oxopropylphosphonate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming identity, purity, and impurity profiles to meet your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.