Description

Methyl 2-Ketobutyrate, 96 CAS NO 3952-66-7 is a high-purity ester derivative of 2-ketobutyric acid, serving as a versatile and critical building block in advanced organic synthesis. This compound is valued for its reactive keto and ester functional groups, which enable precise chemical transformations. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with chiral centers.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators.
• Flavor and Fragrance Industry: Serves as a starting material for creating specific ester-based aroma compounds.
• Organic Chemical Research: Employed as a model substrate in methodological development for esterification, condensation, and reduction reactions.
• Polymer Chemistry: Acts as a monomer or co-monomer in the synthesis of specialized polyesters and other functional polymers.

Basic Information

Product Name	Methyl 2-Ketobutyrate, 96
CAS No.	3952-66-7
Molecular Formula	C5H8O3
Molecular Weight	116.12 g/mol
Synonyms	Methyl 2-oxobutyrate; Methyl acetoacetate, 2-methyl-; 2-Oxobutyric acid methyl ester; Methyl 2-oxobutanoate; Acetic acid, (1-oxopropyl)-, methyl ester; Methyl α-ketobutyrate; Butanoic acid, 2-oxo-, methyl ester
EINECS	223-548-1

Quality Control

Our Methyl 2-Ketobutyrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure it meets the declared purity of 96% and stringent impurity profiles. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment to guarantee traceability and compliance for your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. The container should be kept tightly sealed when not in use to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 96.0%
Water Content (KF)	≤ 0.5%
Refractive Index (20°C)	1.408 - 1.412
Density (20°C)	1.05 - 1.09 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.