Description

Pralidoxime Chloride-003-I is a high-purity pharmaceutical intermediate and active ingredient, specifically a quaternary ammonium oxime salt. This compound is critical for its role as a cholinesterase reactivator, counteracting the effects of certain organophosphate poisoning. It is primarily required by manufacturers in the pharmaceutical and research & development sectors for the production of antidotes and advanced therapeutic agents.

Application

• Pharmaceutical Active Ingredient: Key component in injectable formulations used as an antidote for organophosphate nerve agent and pesticide poisoning.
• Research Chemical: Utilized in biochemical and pharmacological research to study acetylcholinesterase inhibition and reactivation mechanisms.
• Reference Standard: Serves as a high-purity analytical standard for quality control testing in pharmaceutical manufacturing.
• Military & Civil Defense: Incorporated into auto-injector systems and emergency medical kits for chemical weapon countermeasures.
• Veterinary Medicine: Used in formulations to treat organophosphate poisoning in animals.

Basic Information

Product Name	Pralidoxime Chloride-003-I
CAS No.	3861-69-6
Molecular Formula	C7H9ClN2O
Molecular Weight	172.61 g/mol
Synonyms	2-PAM Chloride; Pralidoxime Chloride; Protopam Chloride; 2-Formyl-1-methylpyridinium chloride oxime; 2-Pyridine aldoxime methyl chloride; 2-Hydroxyiminomethyl-1-methylpyridinium chloride; Pralidoxime Cl; 2-Pralidoxime Chloride
EINECS	223-382-8

Quality Control

Our Pralidoxime Chloride-003-I is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product is tested against rigorous in-house specifications, with methods aligned with pharmacopeial standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.