Description

2-Diethoxyphosphoryl-N,n-Dimethylacetamide is a specialized organophosphorus compound that serves as a versatile building block in advanced chemical synthesis. Its unique structure, featuring both phosphoryl and amide functionalities, makes it a valuable reagent for introducing phosphonate groups into target molecules. This chemical is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological pathways.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and plant growth regulators with phosphonate backbones.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphine-based ligands used in catalytic processes.
• Material Science Research: Employed in the development of flame retardants, plasticizers, and other functional additives for polymers.
• Peptide Modification: Used to phosphorylate specific amino acid residues in peptide synthesis for biochemical studies.
• Chemical Biology Probes: Acts as a building block for creating activity-based probes to study enzyme function.

Basic Information

Product Name	2-Diethoxyphosphoryl-N,n-Dimethylacetamide
CAS No.	3842-86-2
Molecular Formula	C8H18NO4P
Molecular Weight	223.21 g/mol
Synonyms	Diethyl (Dimethylcarbamoylmethyl)phosphonate; N,N-Dimethyl-2-(diethoxyphosphoryl)acetamide; Acetamide, 2-(diethoxyphosphinyl)-N,N-dimethyl-; (Dimethylcarbamoylmethyl)phosphonic Acid Diethyl Ester; Diethyl [(Dimethylamino)carbonylmethyl]phosphonate; 2-(Diethoxyphosphoryl)-N,N-dimethylacetamide; Diethyl 2-(Dimethylamino)-2-oxoethylphosphonate; NSC 163047
EINECS	223-345-7

Quality Control

Our 2-Diethoxyphosphoryl-N,n-Dimethylacetamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Density (at 20°C)	~1.10 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.