Description

1,2,2,2-Tetrafluoroethyl Iodide is a versatile fluorinated organic iodide compound, serving as a critical building block for introducing the 1,2,2,2-tetrafluoroethyl group into complex molecules. Its high reactivity, particularly in radical and nucleophilic substitution reactions, makes it a valuable intermediate for synthesizing advanced materials and pharmaceuticals. This compound is essential for researchers and manufacturers in the agrochemical, pharmaceutical, and specialty chemical industries seeking to develop novel fluorinated compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and diagnostic agents that require the 1,2,2,2-tetrafluoroethyl moiety for improved metabolic stability or bioavailability.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides where fluorination enhances biological activity and environmental persistence.
• Advanced Material Production: Building block for fluorinated polymers, liquid crystals, and electronic materials that demand specific dielectric properties and chemical resistance.
• Organic Synthesis Reagent: Employed in radical reactions and cross-coupling chemistry to incorporate fluorinated segments into complex organic frameworks.
• Refrigerant & Propellant Research: Investigated as a potential intermediate or component in next-generation, low-global-warming-potential (GWP) fluorocarbon blends.

Basic Information

Product Name	1,2,2,2-Tetrafluoroethyl Iodide
CAS No.	3831-49-0
Molecular Formula	C2HF4I
Molecular Weight	243.93 g/mol
Synonyms	2,2,2-Tetrafluoroethyl Iodide; Tetrafluoroethyl Iodide; 1-Iodo-1,1,2,2-tetrafluoroethane; Perfluoroethyl Iodide (common misnomer); CF3CHFI; 1,1,2,2-Tetrafluoro-1-iodoethane; Iodotetrafluoroethane
EINECS	223-336-6

Quality Control

Our 1,2,2,2-Tetrafluoroethyl Iodide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical parameters. Our quality commitment ensures the material meets the stringent requirements for research and industrial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place, ideally at 2-8°C (refrigerated) for long-term stability. Keep away from heat, sparks, and open flames. Containers must be kept tightly sealed and upright to prevent leakage and moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.