Description

Picropodophyllol is a specialized organic compound derived from podophyllotoxin, serving as a key intermediate in advanced pharmaceutical synthesis. This high-purity compound is valued for its role in the research and development of novel therapeutic agents, particularly in oncology. It is essential for pharmaceutical manufacturers, research institutions, and fine chemical suppliers engaged in the production of complex active pharmaceutical ingredients (APIs) and investigative new drugs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex anti-cancer agents and other specialized pharmaceuticals.
• Research & Development: Used in medicinal chemistry for the discovery and optimization of new drug candidates targeting various cellular pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating tubulin polymerization inhibition and related mechanisms of action.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis for creating structurally complex molecules with high stereochemical purity.

Basic Information

Item	Detail
Product Name	Picropodophyllol
CAS No.	3811-15-2
Molecular Formula	C22H22O8
Molecular Weight	414.41 g/mol
Synonyms	Picropodophyllin; 5'-Desmethoxy-β-peltatin; NSC 24818; 4-[(1R,2R,3R)-3-(Hydroxymethyl)-5-[(3,4,5-trimethoxyphenyl)methoxy]-7-oxabicyclo[4.1.0]heptan-2-yl]-2,6-dimethoxyphenol; Podophyllotoxin, 5'-desmethoxy-; Isopicropodophyllone
EINECS	Contact for details

Quality Control

Our Picropodophyllol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and related substance determination, to meet the stringent requirements of pharmaceutical-grade intermediates. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.