Description

3-(Trimethylsiloxy)Benzoic Acid Trimethylsilyl Ester is a specialized organosilicon compound that serves as a versatile silylating agent and protected intermediate in advanced organic synthesis. Its core value lies in its ability to introduce trimethylsilyl (TMS) protecting groups for hydroxyl and carboxyl functionalities, enhancing solubility and stability of sensitive molecules during complex reaction sequences. This high-purity reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where precise control over molecular architecture is critical.

Application

• Pharmaceutical Intermediate: Key building block and protecting group reagent in the synthesis of complex active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where silicon-containing intermediates are required.
• Silicon-Based Polymer Chemistry: Acts as a monomer or modifying agent in the synthesis of specialty silicones and siloxane polymers.
• Organic Synthesis Reagent: Employed as a silylating agent to protect reactive functional groups (e.g., -OH, -COOH) in multi-step synthetic routes.
• Material Science Research: Utilized in the development of novel hybrid organic-inorganic materials and surface modifiers.
• Analytical Chemistry: Can be used to derivative compounds for Gas Chromatography-Mass Spectrometry (GC-MS) analysis.

Basic Information

Product Name	3-(Trimethylsiloxy)Benzoic Acid Trimethylsilyl Ester
CAS No.	3782-84-1
Molecular Formula	C13H22O3Si2
Molecular Weight	282.48 g/mol
Synonyms	Benzoic acid, 3-(trimethylsiloxy)-, trimethylsilyl ester; 3-(Trimethylsilyloxy)benzoic acid trimethylsilyl ester; Trimethylsilyl 3-(trimethylsiloxy)benzoate; 3-Hydroxybenzoic acid bis(trimethylsilyl) ether; Bis(trimethylsilyl) 3-hydroxybenzoate; m-(Trimethylsiloxy)benzoic acid TMS ester; TMS-3-TMSOBz; 3-TMSOBz-TMS
EINECS	Contact for details

Quality Control

Our production of 3-(Trimethylsiloxy)Benzoic Acid Trimethylsilyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to confirm identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific tests is provided with every shipment. We support customer audits and can supply material tailored to meet specific project requirements or internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.