Description

β-Estradiol 17-Propionate is a synthetic ester derivative of the natural estrogen hormone, estradiol. This compound is valued for its enhanced stability and controlled release profile compared to the parent hormone, making it a critical intermediate in advanced pharmaceutical synthesis. It is primarily required by manufacturers in the pharmaceutical and life sciences sectors for the development of hormone replacement therapies, veterinary medicines, and research-grade biochemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of steroidal drugs and long-acting hormonal formulations.
• Hormone Replacement Therapy (HRT): Used in the research and development of medications for managing menopausal symptoms and hormonal deficiencies.
• Veterinary Pharmaceuticals: Employed in the production of estrus synchronization agents and growth promoters in animal husbandry.
• Biochemical Research: Serves as a reference standard and active agent in endocrine, metabolic, and cancer research studies.
• Controlled-Release Drug Delivery Systems: Utilized in the design of implants and transdermal patches due to its esterified, lipophilic properties.

Basic Information

Product Name	β-Estradiol 17-Propionate
CAS No.	3758-34-7
Molecular Formula	C21H28O3
Molecular Weight	328.45 g/mol
Synonyms	Estradiol 17-Propionate; 17β-Estradiol 17-Propionate; Oestradiol Propionate; Estradiol Propanoate; NSC 17591; (17β)-Estra-1,3,5(10)-triene-3,17-diol 17-propanoate; E2 Propionate
EINECS	223-157-8

Quality Control

Our β-Estradiol 17-Propionate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, IR for identification, and residual solvent analysis, to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.