Description

2-Amino-4-[p-[Bis(2-Chloroethyl)Amino]Phenyl]Butyric Acid is a specialized amino acid derivative of significant interest in advanced pharmaceutical research and development. This compound matters as a key synthetic intermediate, particularly in the design and synthesis of targeted therapeutic agents, due to its unique bifunctional structure combining a phenylalanine-like backbone with a nitrogen mustard moiety. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in oncology drug discovery, prodrug development, and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of experimental chemotherapeutic agents and targeted cancer therapies.
• Prodrug Development: Used in research for designing prodrugs that can be selectively activated in specific physiological environments.
• Bioconjugation: Acts as a linker molecule for attaching cytotoxic payloads to antibodies, peptides, or other targeting ligands in Antibody-Drug Conjugate (ADC) research.
• Medicinal Chemistry Research: Provides a versatile scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Biochemical Tool Compound: Employed in laboratory studies to investigate alkylating agent mechanisms and DNA interaction studies.
• Fine Chemical Synthesis: Used as a precursor for the preparation of more complex, functionally diverse organic molecules.

Basic Information

Product Name	2-Amino-4-[p-[Bis(2-Chloroethyl)Amino]Phenyl]Butyric Acid
CAS No.	3688-35-5
Molecular Formula	C14H20Cl2N2O2
Molecular Weight	319.23 g/mol
Synonyms	DL-4-[p-[Bis(2-chloroethyl)amino]phenyl]-2-aminobutyric acid; NSC 172112; Phenylalanine nitrogen mustard; 4-[p-[Bis(2-chloroethyl)amino]phenyl]-2-aminobutanoic acid; 2-Amino-4-(4-[bis(2-chloroethyl)amino]phenyl)butanoic acid; CB 3004; L-Phenylalanine mustard analogue
EINECS	Contact for details

Quality Control

Our 2-Amino-4-[p-[Bis(2-Chloroethyl)Amino]Phenyl]Butyric Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.