Description

cis-Ethyl 4-Aminocyclohexanecarboxylate is a versatile chiral building block and intermediate of significant importance in advanced organic synthesis. Its value lies in the cis-configured amino and ester functional groups on the cyclohexane ring, which are crucial for constructing complex molecules with specific stereochemistry. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting neurological and cardiovascular diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators where stereochemistry impacts biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and performance materials requiring a rigid, functionalized cyclohexane scaffold.
• Academic and R&D: A valuable compound for methodological studies in organic chemistry, particularly in stereoselective synthesis and ring transformation reactions.

Basic Information

Product Name	cis-Ethyl 4-Aminocyclohexanecarboxylate
CAS No.	3685-28-7
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	Ethyl cis-4-aminocyclohexanecarboxylate; 4-Aminocyclohexanecarboxylic Acid Ethyl Ester, cis-; cis-4-(Ethoxycarbonyl)cyclohexylamine; 4-Amino-1-cyclohexanecarboxylic Acid Ethyl Ester; Ethyl 4-Aminocyclohexanecarboxylate (cis isomer); UNII-8JQ5607IO5; 1-Cyclohexanecarboxylic acid, 4-amino-, ethyl ester, cis-; 4-Aminocyclohexanecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our cis-Ethyl 4-Aminocyclohexanecarboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and isomeric consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee reliable and reproducible performance in your synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (cis-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.