Description

2-Chloro-4-Picoline is a versatile halogenated pyridine derivative, serving as a crucial building block in advanced organic synthesis. Its value lies in the strategic reactivity of the chlorine atom and the methyl group, enabling precise molecular modifications. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the pyridine core provides bioactivity.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and functional polymers.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry and process chemistry in exploring new chemical entities.
• Dye and Pigment Intermediate: Used in the synthesis of complex colorants and photographic chemicals.

Basic Information

Product Name	2-Chloro-4-Picoline
CAS No.	3678-62-4
Molecular Formula	C6H6ClN
Molecular Weight	127.57 g/mol
Synonyms	2-Chloro-4-methylpyridine; 4-Methyl-2-chloropyridine; 2-Chloro-4-picoline; 2-Chloro-γ-picoline; 4-Picoline, 2-chloro-; 2-Chloro-4-methylpyridine (primary synonym); 2-Cl-4-Mepy
EINECS	222-964-3

Quality Control

Our 2-Chloro-4-Picoline is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including GC/HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.