Description

Methanesulfonyl Isocyanate is a highly reactive organic compound primarily used as a versatile sulfonylating and carbonylating agent in chemical synthesis. Its value lies in its ability to efficiently introduce the methanesulfonyl (mesyl) group into target molecules, a key step in producing pharmaceuticals, agrochemicals, and advanced materials. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonylurea and sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of modern herbicides and pesticides, where the sulfonyl isocyanate moiety contributes to biological activity.
• Polymer Modification: Serves as a functional monomer or cross-linking agent to introduce reactive isocyanate groups into polymer chains, enhancing material properties.
• Peptide Chemistry: Employed as a coupling reagent or for the selective modification of amino acid side chains during peptide synthesis.
• Chemical Research & Development: A valuable reagent for exploring new synthetic pathways and creating novel chemical entities in academic and industrial labs.
• Dye and Pigment Manufacturing: Used in the synthesis of specialized colorants and functional dyes that require sulfonamide linkages.

Basic Information

Product Name	Methanesulfonyl Isocyanate
CAS No.	3611-92-5
Molecular Formula	C2H3NO3S
Molecular Weight	121.11 g/mol
Synonyms	Methanesulfonic Acid Isocyanate; Methylsulfonyl Isocyanate; Isocyanatomethanesulfonyl; Mesyl Isocyanate; Methanesulphonyl Isocyanate; NSC 163063; Methane sulfonyl isocyanate; Isocyanic Acid Methanesulfonyl Ester
EINECS	Contact for details

Quality Control

Our Methanesulfonyl Isocyanate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including assay (by titration or HPLC), identity confirmation (IR), and impurity profiling, to ensure it meets the high-purity standards required for synthetic applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its moisture-sensitive (hygroscopic) nature, containers must be kept tightly sealed under a dry inert atmosphere (e.g., nitrogen) to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as water, alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.