Description

Leucine, n-(n-Acetyl-3-(p-(Bis(2-Chloroethyl)Amino)Phenyl)-Dl-Alanyl)- , Ethyl Ester, L- is a specialized, high-purity synthetic amino acid derivative with a complex molecular architecture. This compound matters as a critical building block and key intermediate in advanced pharmaceutical research and development, particularly for targeted therapies. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors for synthesizing novel bioactive peptides and investigating potential chemotherapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex peptide-based drug candidates and targeted chemotherapeutic agents.
• Biochemical Research: Used as a specialized substrate or inhibitor in enzymatic studies and proteomics research to investigate biological pathways.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis for creating custom sequences.
• Anticancer Agent Research: Investigated for its potential role as a nitrogen mustard-bearing amino acid analog in experimental oncology studies.
• Prodrug Development: Utilized in the design and development of prodrugs aimed at improving drug targeting and bioavailability.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	Leucine, n-(n-Acetyl-3-(p-(Bis(2-Chloroethyl)Amino)Phenyl)-Dl-Alanyl)- , Ethyl Ester, L-
CAS No.	3577-89-7
Molecular Formula	C25H39Cl2N3O5
Molecular Weight	532.50 g/mol
Synonyms	L-N-Acetyl-melphalan ethyl ester; N-Acetyl-L-melphalan ethyl ester; L-N-Acetyl-3-[p-[bis(2-chloroethyl)amino]phenyl]alanine ethyl ester; Nα-Acetyl-melphalan ethyl ester; Ac-Melphalan-OEt; N-Acetyl-melphalan O-ethyl ester; [N-Acetyl-3-(p-[bis(2-chloroethyl)amino]phenyl)alanyl] leucine ethyl ester (related peptide derivative); L-Form of the acetylated ethyl ester of the phenylalanine nitrogen mustard derivative
EINECS	Contact for details

Quality Control

Our Leucine, n-(n-Acetyl-3-(p-(Bis(2-Chloroethyl)Amino)Phenyl)-Dl-Alanyl)- , Ethyl Ester, L- is manufactured under strict controls to ensure high purity and batch-to-batch consistency suitable for research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed in a dry environment to minimize moisture uptake. Handle and store in accordance with all applicable laboratory safety regulations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.