Description

Butylthiotrimethylsilane is a versatile organosilicon reagent featuring a sulfur-silicon bond, widely used as a silylating agent and synthetic intermediate. Its primary value lies in its ability to introduce the tert-butyldimethylsilyl (TBDMS) protecting group for alcohols and thiols, offering superior stability under various reaction conditions compared to other silyl ethers. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where precise protection and deprotection steps are critical for synthesizing complex molecules.

Application

• As a silylating agent for the protection of hydroxyl (-OH) and thiol (-SH) groups in multi-step organic synthesis.
• Key intermediate in the production of active pharmaceutical ingredients (APIs) and fine chemicals.
• Used in the synthesis of liquid crystals and other advanced organic electronic materials.
• Employed as a reagent in polymer modification and surface functionalization.
• Facilitates the synthesis of flavor and fragrance compounds requiring selective protection strategies.
• Utilized in agrochemical research for the development of novel pesticides and herbicides.

Basic Information

Product Name	Butylthiotrimethylsilane
CAS No.	3553-78-4
Molecular Formula	C7H18SSi
Molecular Weight	162.37 g/mol
Synonyms	tert-Butyldimethylsilyl Sulfide; tert-Butyldimethylsilanethiol; TBDMS Sulfide; (tert-Butyldimethylsilyl)thio; tert-Butyl(dimethyl)silyl Sulfide; tert-Butyldimethylsilyl Mercaptan; tert-Butyldimethylsilanethiolate; 1,1-Dimethylethyl(dimethyl)silanethiol
EINECS	222-603-8

Quality Control

Our Butylthiotrimethylsilane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.