Description

(25R)-2α,3β-Dihydroxy-5α-Spirost-9(11)-En-12-One is a high-purity, steroidal sapogenin derivative characterized by its specific stereochemistry at the C-25 position. This compound serves as a critical advanced pharmaceutical intermediate and a versatile scaffold for the synthesis of novel bioactive molecules. It is primarily required by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in steroid chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of steroidal drugs and novel therapeutic agents.
• Biochemical Research: Used as a reference standard and building block in studies of steroid metabolism, receptor binding, and biological activity.
• Organic Synthesis: A versatile chiral template for constructing complex natural products and exploring new synthetic methodologies in organic chemistry.
• Academic & Industrial R&D: Fundamental compound for investigating structure-activity relationships (SAR) and developing new chemical entities.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals and advanced materials.

Basic Information

Product Name	(25R)-2α,3β-Dihydroxy-5α-Spirost-9(11)-En-12-One
CAS No.	3514-48-5
Molecular Formula	C27H40O5
Molecular Weight	444.61 g/mol
Synonyms	2α,3β-Dihydroxy-5α-spirost-9(11)-en-12-one; (25R)-Spirost-9(11)-en-12-one, 2,3-dihydroxy-, (2α,3β,5α,25R)-; 12-Ketone of diosgenin derivative; 9(11)-Dehydro derivative of tigogenin; 2α,3β-Dihydroxytigogenone; Tigogenone derivative; 5α-Spirost-9(11)-en-12-one-2α,3β-diol
EINECS	Contact for details

Quality Control

Our (25R)-2α,3β-Dihydroxy-5α-Spirost-9(11)-En-12-One is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to reliable supply and traceability supports your R&D and production timelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.