Description

Methyl 2-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-β-D-Mannopyranoside CAS NO 3504-69-6 is a fully protected derivative of methyl α-D-mannopyranoside, where all hydroxyl groups are silylated with trimethylsilyl (TMS) groups. This chemical modification is critical for its role as a key synthetic intermediate and protecting group strategy in complex carbohydrate and nucleoside chemistry. It is primarily utilized by research scientists and process chemists in the pharmaceutical, biotechnology, and fine chemical sectors for the development of glycosylated compounds, glycoconjugates, and other bioactive molecules.

Application

• Glycosylation Reactions: Serves as a crucial mannosyl donor or acceptor in the stereoselective synthesis of oligosaccharides and complex glycans.
• Pharmaceutical Intermediate: Used in the research and development of novel glycoprotein drugs, antiviral agents, and carbohydrate-based vaccines.
• Protecting Group Chemistry: The TMS groups provide orthogonal protection, allowing for selective deprotection and further functionalization at specific positions on the sugar ring.
• Chemical Biology Research: A valuable tool for studying carbohydrate-protein interactions, enzyme mechanisms, and metabolic pathways.
• Fine Chemical Synthesis: Employed in the production of specialized chiral building blocks, flavors, and fragrances requiring high stereochemical purity.
• Material Science: Potential use in the synthesis of carbohydrate-based polymers and surface modifiers.

Basic Information

Product Name	Methyl 2-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-β-D-Mannopyranoside
CAS No.	3504-69-6
Molecular Formula	C19H46O6Si4
Molecular Weight	482.90 g/mol
Synonyms	Methyl 2,3,4,6-Tetra-O-trimethylsilyl-β-D-mannopyranoside; Methyl β-D-Mannopyranoside Tetrakis(trimethylsilyl) Ether; 1-Methoxy-2,3,4,6-tetra-O-(trimethylsilyl)-β-D-mannopyranose; TMS-protected Methyl Mannoside; Methyl O-(Trimethylsilyl)mannoside; β-D-Mannopyranoside, methyl 2,3,4,6-tetrakis-O-(trimethylsilyl)-
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-β-D-Mannopyranoside is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing specific batch results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (GC)	≥ 90.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.