Description

Clidinium Bromide CAS NO 3485-62-9 is a quaternary ammonium anticholinergic agent, primarily recognized for its potent antimuscarinic and antispasmodic properties. This compound is a critical active pharmaceutical ingredient (API) used in the formulation of medications designed to treat gastrointestinal disorders. It is essential for pharmaceutical manufacturers and research institutions focused on developing treatments for conditions like irritable bowel syndrome and peptic ulcers. The product's efficacy is derived from its specific action on smooth muscle and glandular secretions within the digestive tract.

Application

• Pharmaceutical API: Primary use as the active ingredient in antispasmodic and antisecretory medications.
• Gastrointestinal Therapeutics: Formulation of drugs for treating irritable bowel syndrome (IBS) and associated abdominal cramps.
• Peptic Ulcer Adjunct Therapy: Used in combination with other agents to reduce gastric acid secretion and intestinal motility.
• Clinical Research: Serves as a reference standard and key intermediate in pharmacological R&D for anticholinergic drugs.
• Veterinary Medicine: Potential application in veterinary pharmaceuticals for managing gastrointestinal hypermotility in animals.

Basic Information

Product Name	Clidinium Bromide
CAS No.	3485-62-9
Molecular Formula	C22H26BrNO3
Molecular Weight	432.35 g/mol
Synonyms	Clidinium Bromide; 3-Hydroxy-1-methylquinuclidinium bromide benzilate; Quarzan; (3-Hydroxy-1-methylquinuclidinium) benzilate bromide; 1-Methyl-3-hydroxyquinuclidinium bromide benzilate; Librax component; Clidinio bromuro; Clidiniumbromid
EINECS	222-491-3

Quality Control

Our Clidinium Bromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide detailed Certificates of Analysis (COA) that include results for identity, assay, purity, and specified impurities. Quality is assured through compliance with ICH guidelines and relevant pharmacopeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.