Description

Cholesteryl Chloroacetate CAS NO 3464-50-4 is a high-purity cholesterol derivative where the hydroxyl group is esterified with chloroacetic acid. This modification is critical for introducing reactive functionality into the cholesterol backbone, making it a versatile intermediate for advanced chemical synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, liquid crystal, and specialty chemical industries for developing novel compounds and materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of steroidal drugs, prodrugs, and targeted therapeutic agents.
• Liquid Crystal Material: Used in the research and development of cholesteric liquid crystals for displays and optical devices.
• Bioconjugation & Probe Synthesis: Serves as a reactive handle for attaching cholesterol to peptides, proteins, or fluorescent labels for biological studies.
• Polymer & Material Science: Acts as a functional monomer or additive to modify the properties of polymers and advanced materials.
• Chemical Research: Essential reagent in organic synthesis for creating complex steroidal architectures and exploring new reaction pathways.

Basic Information

Product Name	Cholesteryl Chloroacetate
CAS No.	3464-50-4
Molecular Formula	C29H47ClO2
Molecular Weight	463.14 g/mol
Synonyms	Cholest-5-en-3β-yl chloroacetate; 3β-Cholest-5-en-3-yl chloroacetate; Cholesterol chloroacetate; Chloroacetic acid cholesteryl ester; (3β)-Cholest-5-en-3-yl 2-chloroacetate
EINECS	222-400-8

Quality Control

Our Cholesteryl Chloroacetate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency. Each lot is analyzed using advanced techniques including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.