Description

Folitixorin (Mixture Of Diastereomers) is a chemically defined form of folinic acid, a vital biochemical intermediate. This high-purity compound is essential for research and development in advanced pharmaceutical synthesis, particularly where precise stereochemistry is a critical factor. It serves as a key building block for scientists and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors requiring a reliable source of this specific active pharmaceutical ingredient (API) intermediate.

Application

• Pharmaceutical Intermediate: Critical starting material or intermediate in the synthesis of advanced chemotherapeutic agents and other specialty pharmaceuticals.
• Biochemical Research: Used in enzymatic studies and metabolic pathway research as a source of active folate.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Cell Culture & Media Supplement: Potential application in specialized cell culture media formulations requiring defined folate sources.
• Process Development: Employed in the development and scale-up of synthetic routes for folate-based drugs.
• Antidote Formulation Research: Investigated in research related to antidotes for certain chemotherapeutic agents (e.g., methotrexate rescue).

Basic Information

Product Name	Folitixorin (Mixture Of Diastereomers)
CAS No.	3432-99-3
Molecular Formula	C₂₀H₂₃N₇O₇
Molecular Weight	473.45 g/mol
Synonyms	Folinic Acid, Mixture of Diastereomers; 5-Formyltetrahydrofolate; 5-CHO-THF; Leucovorin, Diastereomeric Mixture; Citrovorum Factor; (6S)- and (6R)-5-Formyl-5,6,7,8-tetrahydrofolic Acid; NSC-3590; Calcium Folinate (mixture)
EINECS	222-321-9

Quality Control

Our Folitixorin (Mixture Of Diastereomers) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and diastereomeric ratio, and identification by IR and NMR spectroscopy, to ensure it meets stringent specifications for pharmaceutical R&D use. A Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0% (anhydrous basis)
Diastereomeric Ratio (HPLC)	Specified per grade
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.