Description

2'-Hydroxy-4,4',6'-Trimethoxychalcone is a specialized chalcone derivative, a class of organic compounds known for their diverse biological activities. This compound matters as a high-value synthetic intermediate and a key scaffold in pharmaceutical and agrochemical research, offering a versatile platform for chemical modification. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, nutraceutical, and fine chemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a core building block for synthesizing novel drug candidates with potential anti-inflammatory, antioxidant, or anticancer properties.
• Biochemical Research: Used as a reference standard or probe in studying enzyme inhibition, signal transduction pathways, and other biological mechanisms.
• Agrochemical Development: Acts as a precursor in the synthesis of new plant growth regulators or crop protection agents.
• Cosmetic Ingredient Synthesis: Employed in the development of skin-care active ingredients targeting oxidative stress or inflammation.
• Material Science: Investigated as a monomer or additive for creating functional polymers with specific optical or electronic properties.

Basic Information

Product Name	2'-Hydroxy-4,4',6'-Trimethoxychalcone
CAS No.	3420-72-2
Molecular Formula	C₁₈H₁₈O₆
Molecular Weight	330.33 g/mol
Synonyms	2'-Hydroxy-4,4',6'-trimethoxychalcone; (E)-1-(2-Hydroxyphenyl)-3-(2,4,6-trimethoxyphenyl)prop-2-en-1-one; 2',4,4',6-Tetramethoxychalcone (common misnomer); NSC 407347; Chalcone, 2'-hydroxy-4,4',6'-trimethoxy-; 3-(2,4,6-Trimethoxyphenyl)-1-(2-hydroxyphenyl)-2-propen-1-one
EINECS	Contact for details

Quality Control

Our 2'-Hydroxy-4,4',6'-Trimethoxychalcone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and physical characteristics. Our quality system supports development and commercial needs, from laboratory research to pilot-scale cGMP production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.