Description

Z-D-Phe-Osu CAS NO 3397-36-2 is a high-purity, activated ester derivative of N-Carbobenzoxy-D-phenylalanine, designed for efficient peptide synthesis. This compound is a critical building block for researchers and manufacturers requiring precise, racemization-free coupling in complex organic and peptide chemistry. It is primarily utilized in the pharmaceutical and biotechnology sectors for the development of active pharmaceutical ingredients (APIs), peptide-based drugs, and advanced research reagents.

Application

• Peptide Synthesis: A key reagent for the solid-phase and solution-phase synthesis of peptides, facilitating the incorporation of D-phenylalanine residues.
• Pharmaceutical Intermediates: Serves as a crucial intermediate in the production of peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Bioconjugation: Used in the modification of proteins, antibodies, and other biomolecules for research and diagnostic applications.
• Organic Synthesis: Acts as a protected amino acid derivative in complex multi-step organic syntheses for novel chemical entities.
• Proteomics Research: Employed in the study of enzyme inhibitors and the development of peptide probes for biochemical assays.
• Academic & Industrial R&D: A fundamental tool in research laboratories for exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	Z-D-Phe-Osu
CAS No.	3397-36-2
Molecular Formula	C20H20N2O6
Molecular Weight	384.39 g/mol
Synonyms	N-Carbobenzoxy-D-phenylalanine N-hydroxysuccinimide ester; Z-D-Phenylalanine N-succinimidyl ester; Z-D-Phe-OSu; N-(Benzyloxycarbonyl)-D-phenylalanine N-hydroxysuccinimide ester; D-Phenylalanine, N-[(phenylmethoxy)carbonyl]-, 1,2,3,6-tetrahydro-2,5-dioxo-3-furanylmethyl ester; CBZ-D-Phe-OSu; NSC 334381; Benzyloxycarbonyl-D-phenylalanine N-hydroxysuccinimide ester
EINECS	Contact for details

Quality Control

Our Z-D-Phe-Osu is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and chiral purity, to meet the stringent requirements of pharmaceutical and research applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% D-isomer
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.