Description

Boc-Ile-Osu CAS NO 3392-08-3 is a high-purity, protected amino acid derivative, specifically N-(tert-Butoxycarbonyl)-L-isoleucine N-hydroxysuccinimide ester. This compound serves as a critical building block in solid-phase peptide synthesis (SPPS), enabling the efficient and selective incorporation of isoleucine into peptide chains. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing novel therapeutic peptides, APIs, and biochemical probes.

Application

• Peptide Synthesis: A key reagent for the controlled, racemization-free coupling of Boc-protected isoleucine in both solution-phase and solid-phase peptide synthesis (SPPS).
• Pharmaceutical Intermediates: Used in the research and production of active pharmaceutical ingredients (APIs) for peptide-based drugs targeting metabolic disorders, oncology, and infectious diseases.
• Bioconjugation: Facilitates the site-specific labeling and modification of proteins, antibodies, and other biomolecules for diagnostic and research applications.
• Combinatorial Chemistry: Employed in the generation of diverse peptide libraries for high-throughput screening in drug discovery programs.
• Academic & Industrial Research: A fundamental tool in biochemistry and molecular biology laboratories for studying protein structure, function, and interactions.
• Custom Oligopeptide Production: Used by CROs and CDMOs specializing in the synthesis of custom peptides for clients worldwide.

Basic Information

Item	Detail
Product Name	Boc-Ile-Osu
CAS No.	3392-08-3
Molecular Formula	C15H24N2O6
Molecular Weight	328.36 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-L-isoleucine N-hydroxysuccinimide ester; Boc-L-isoleucine-OSu; Boc-Ile-OSu; N-Boc-L-isoleucine N-succinimidyl ester; N-α-Boc-L-isoleucine N-hydroxysuccinimide ester; N-(tert-Butoxycarbonyl)isoleucine N-hydroxysuccinimide ester; BOC-ILE-OSU; tert-Butyloxycarbonyl-L-isoleucine N-oxysuccinimide ester
EINECS	Contact for details

Quality Control

Our Boc-Ile-Osu is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric integrity, and identity confirmation via spectroscopic methods. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.5%
Optical Rotation [α]	Specific range provided on COA
Melting Point	Specific range provided on COA
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.