Description

Sodium 5-(2-Bromoallyl)-5-Isopropyl-1-Methylbarbiturate is a specialized barbiturate derivative salt, serving as a critical pharmaceutical intermediate and synthetic building block. Its value lies in its unique bromoallyl and isopropyl substituents, which provide a reactive handle for further chemical modifications and influence the pharmacokinetic properties of final active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and fine chemical sectors, particularly those developing central nervous system (CNS) agents, sedatives, or novel therapeutic compounds.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the manufacture of barbiturate-based active pharmaceutical ingredients (APIs) and potential CNS drugs.
• Medicinal Chemistry Research: Valuable building block for structure-activity relationship (SAR) studies and the development of new therapeutic candidates with modified barbiturate cores.
• Chemical Synthesis: Utilized in organic synthesis for introducing the barbiturate moiety into more complex molecular architectures, leveraging the reactivity of the bromoallyl group.
• Process Development & Scale-Up: Serves as a standardized starting material for optimizing synthetic routes and scaling production in fine chemical manufacturing.
• Reference Standard: Used in analytical laboratories as a high-purity standard for quality control, method development, and regulatory compliance testing of related substances.

Basic Information

Product Name	Sodium 5-(2-Bromoallyl)-5-Isopropyl-1-Methylbarbiturate
CAS No.	3329-16-6
Molecular Formula	C11H15BrN2NaO3
Molecular Weight	323.15 g/mol
Synonyms	5-(2-Bromoallyl)-5-isopropyl-1-methylbarbituric acid sodium salt; Sodium 5-(2-bromo-2-propenyl)-5-(1-methylethyl)-1-methyl-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-Isopropyl-5-(2-bromoallyl)-1-methylbarbituric acid sodium salt; 1-Methyl-5-isopropyl-5-(2-bromoallyl)barbituric acid sodium salt; Sodium 5-isopropyl-1-methyl-5-(2-bromoallyl)barbiturate; Barbituric acid derivative, sodium salt; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Sodium 5-(2-Bromoallyl)-5-Isopropyl-1-Methylbarbiturate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.