Description

Tms-α-D-(+)-Glucose CAS NO 3327-61-5 is a trimethylsilyl (TMS) derivative of the fundamental monosaccharide, α-D-glucose, designed for advanced analytical and synthetic applications. This compound is critical for researchers and manufacturers requiring precise derivatization to enhance volatility and stability for gas chromatography (GC) and mass spectrometry (MS) analysis. It serves as a key intermediate and reference standard in pharmaceutical research, carbohydrate chemistry, and the development of diagnostic reagents.

Application

• Gas Chromatography (GC) and GC-MS Analysis: Used as a derivatization agent to improve the volatility and thermal stability of sugars and related compounds for accurate identification and quantification.
• Pharmaceutical Reference Standard: Employed as a high-purity standard in quality control and method development for drug substances and excipients derived from carbohydrates.
• Carbohydrate Chemistry Research: Serves as a protected building block or intermediate in the synthesis of complex oligosaccharides, glycoconjugates, and novel sugar derivatives.
• Metabolomics and Biochemical Profiling: Acts as a critical reagent for the analysis of metabolic pathways involving glucose and its derivatives in biological systems.
• Diagnostic Reagent Manufacturing: Utilized in the production of reagents and kits for clinical diagnostics, particularly those targeting carbohydrate metabolism disorders.
• Academic and Industrial R&D: Provides a versatile tool for spectroscopic studies, reaction mechanism investigations, and the development of new analytical methodologies.

Basic Information

Product Name	Tms-α-D-(+)-Glucose
CAS No.	3327-61-5
Molecular Formula	C15H36O6Si3
Molecular Weight	396.70 g/mol
Synonyms	1,2,3,4,6-Penta-O-trimethylsilyl-α-D-glucopyranose; α-D-Glucose penta(trimethylsilyl) ether; Penta-O-trimethylsilyl-α-D-glucopyranose; TMS-α-D-Glucose; α-D-Glucose, penta-TMS derivative; Trimethylsilyl α-D-glucopyranoside (penta); α-D-Glucopyranose, 1,2,3,4,6-penta-O-(trimethylsilyl)-
EINECS	Contact for details

Quality Control

Our Tms-α-D-(+)-Glucose is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality systems support compliance with cGMP and ISO standards for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can compromise product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC or HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.