Description

Diethyl 5-Hydroxy-6-Methylpyridine-3,4-Dicarboxylate Hydrochloride is a high-purity pyridine derivative salt, serving as a critical pharmaceutical intermediate and versatile building block in organic synthesis. Its value lies in its functionalized structure, which is essential for constructing complex molecules in medicinal chemistry and advanced material science. This compound is primarily needed by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and metabolic pathways.
• Organic Synthesis Building Block: Utilized in the construction of heterocyclic compounds, ligands for catalysis, and advanced organic materials.
• Research & Development (R&D): Serves as a standard or starting material in academic and industrial research for novel compound libraries.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides due to its pyridine core.
• Coordination Chemistry: Acts as a potential ligand for metal complexes in catalytic applications.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional additives.

Basic Information

Product Name	Diethyl 5-Hydroxy-6-Methylpyridine-3,4-Dicarboxylate Hydrochloride
CAS No.	3307-86-6
Molecular Formula	C12H15NO5 • HCl
Molecular Weight	289.71 g/mol (Free base: 253.25 g/mol)
Synonyms	5-Hydroxy-6-methylpyridine-3,4-dicarboxylic acid diethyl ester hydrochloride; Diethyl 5-hydroxy-6-methyl-3,4-pyridinedicarboxylate hydrochloride; 3,4-Pyridinedicarboxylic acid, 5-hydroxy-6-methyl-, diethyl ester, hydrochloride; 5-Hydroxy-6-methyl-3,4-pyridinedicarboxylic acid diethyl ester HCl; Ethyl 5-hydroxy-6-methylnicotinate hydrochloride derivative; Pyridine dicarboxylate ester hydrochloride.
EINECS	Contact for details

Quality Control

Our Diethyl 5-Hydroxy-6-Methylpyridine-3,4-Dicarboxylate Hydrochloride is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.