Description

3-(4-Bromo-Phenyl)-2-Cyano-3-Oxo-Propionic Acid tert-Butyl Ester is a high-value, versatile chemical intermediate characterized by its bromophenyl and cyano-keto ester functional groups. This compound matters for its role as a critical building block in the synthesis of complex organic molecules, enabling the introduction of multiple reactive sites for further chemical elaboration. It is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing bromoaryl and cyano functional motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its reactive ester and nitrile groups.
• Organic Synthesis Building Block: Serves as a versatile synthon in academic and industrial research for constructing complex heterocycles and fine chemicals via reactions like Knoevenagel condensation or nucleophilic substitution.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, or organic electronic materials due to its aromatic and polarizable structure.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions in manufacturing processes.

Basic Information

Product Name	3-(4-Bromo-Phenyl)-2-Cyano-3-Oxo-Propionic Acid tert-Butyl Ester
CAS No.	3239-81-4
Molecular Formula	C14H14BrNO3
Molecular Weight	324.17 g/mol
Synonyms	tert-Butyl 3-(4-bromophenyl)-2-cyano-3-oxopropanoate; 2-Cyano-3-(4-bromophenyl)-3-oxopropanoic Acid tert-Butyl Ester; 3-Oxo-3-(4-bromophenyl)-2-cyano-propionic Acid tert-Butyl Ester; 4-Bromo-α-cyanoacetophenone tert-Butyl Ester; (4-Bromobenzoyl)acetonitrile tert-Butyl Ester; 3-(p-Bromophenyl)-2-cyano-3-oxopropionic Acid tert-Butyl Ester; 3239-81-4; Propanoic acid, 3-(4-bromophenyl)-2-cyano-3-oxo-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 3-(4-Bromo-Phenyl)-2-Cyano-3-Oxo-Propionic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong bases, strong oxidizing agents, and strong reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.